Oxytetracycline is a tetracycline antimicrobial drug sometimes used to treat bacterial infections caused by Pasteurella multocida
(Fowl cholera), Mycoplasma spp
, Salmonella typhimurium
(Paratyphoid), Chlamydophila psittaci
, and Escherichia coli
in poultry. Oxytetracycline has also been used for prevention of coccidiosis, caused by E. tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti
, and E. mivati
Egg Withdrawal Period:
- In Canada: Oxytetracycline soluble powder is approved for use in the drinking water of laying hens at concentrations ranging from 50 to 112 mg/L (190 to 424 mg/gal) with 60-hour to 5-day egg withdrawal intervals, respectively.
- Other countries: Varies from 7 to 21 days.
Prolonged treatment can have catabolic and immunosuppressive effects, reduce normal gut flora, and cause the bird to become more susceptible to opportunistic secondary infections. When injected, it can cause tissue necrosis at the injection site.