Brand Names:
Suprelorin


Drug Type: GnRH-agonist, Hormones

Deslorelin (Suprelorin)


Deslorelin (Suprelorin) is a peptide-based, non-steroidal contracepative gonadotropin-releasing hormone (GnRH) agonist implant whose effect is to mimic overproduction of GnRH, thus suppressing the function of the pituitary-gonadal axis. In doing so, it decreases the production of the luteinising hormone (LH) and follicle stimulating hormone (FSH). This helps to prevent the hen from ovulating (laying eggs).

How are Deslorelin implants Inserted?


Deslorelin implants come in two strengths---4.7mg and 9.4mg, which are easily inserted subcutaneously or intramuscularly over the hen's pectoral muscle by your veterinarian.

Once inserted, the implant may take about 2 to 6 weeks to take effect. About 70% of hens who receive the implant will stop laying eggs (although the effects are temporarily). Hens who receive the 4.7mg implant will usually stop laying eggs for an average of 161 days. When two 4.7mg implants are used, the effects last 207 days. When the 9.4mg implant is used, the effects may last up to 385 days, until which time they will require another implant.

How it Works


Once given to the bird, the implant releases deslorelin into the bird's system gradually, over the course of several months. Deslorelin blocks the production of follicle stimulating hormone (FSH) and luteinising hormone (LH) in implanted birds. This results in less testosterone circulating in the bird's blood which in turn, decreases egg production.
  • Moulting
  • Weight loss
  • Behavior changes
  • Swelling at the implant site for two weeks following the implantation.
  • Local reaction in the form of inflammation or hardening at the site for up to 3 months after implantation.