Amprolium is a common anticoccidial medication used in the treatment and prevention of coccidiosis
in chickens and turkeys. In the United States, it is one of the few medications approved by the FDA for use in egg laying hens. There is no withdrawal period. Amprolium works by mimicking thiamine (Vitamin B1), which is what cocci require to grow and reproduce inside the chicken. When cocci ingest amprolium, they experience thiamin deficiency and starve from malnutrition. This is why it's important not to administer Vitamin B1 to chickens who are concurrently being treated with amprolium.
There are several different brands of Amprolium available. These include:
- CORID 20% Soluble Powder - (United States) Can be given as a 21-day preventative or a 5-day treatment. It is mixed into the flock's water source. There is 200 mg of amprolium in every 1 gram of this medication.
- CORID 9.6% Oral Solution - (United States) This product is available as a 1 gallon or 16 oz bottle. Can be given as a 21-day preventative or a 5-day treatment. It is mixed into the flock's water source. There are 96 mg of amprolium in every 1 mL of CORID 9.6% Solution.
- Amprolin-300 WS - Comes as a water-soluble powder and mixed into the drinking water. It can be given as a preventative or treatment. For prevention, it is given at 1 kg per 5000 L of water, for 1-2 weeks. As a treatment, it is given at 1 kg per 1250 to 2500 L of water for 5-7 days. There is a withdrawal time of 3 days.
- AmproMed P for Poultry, 9.6% Oral Solution - (United States) An oral solution intended to be mixed in the water as a preventative or treatment. For prevention, it is given in the water at 0.012% for 3-5 days (8 fl oz of the product per 50 gallons of water), or as a treatment 0.024% (16 fl oz of the product in 5 gallons of water) for 3-5 days. Then, continue with 0.006% (4 fl oz of the product in 5 gallons of water) for an additional 1-2 weeks.
- Coxoid- (United Kingdom) Available in two sizes--112 mL or 500 mL bottle. Given in the flock's drinking water at a rate of 28 mL per 4.5 L (1 fl oz per gallon) as a treatment for 7 days. In serious outbreaks, should be given for an additional 7 days at half strength (14 mL per 4.5 liters).
: Amprolium has a very narrow margin for error and overdoses can lead to hemorrhagic diathesis and death. Should not be given to chickens concurrently with any B Vitamins.
Chicks on a diet of medicated starter feed should NOT be administered any additional coccidiosis medications. It can result in Thiamine deficiency
Make drinking water fresh daily. Any medicated water which is not consumed within 24 hours should be discarded. Stock solutions for proportioners may be stored in a clean, closed labeled container for up to 3 days. Store between 5°-25°C (41°-77°F) with brief excursions to 40°C. The shelf life of the drug is 5 years from the date of manufacture.