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Ovarian Cancer

Oviductal Adenocarcinoma, Reproductive Tract Tumor

Laying hens are prone to spontaneous development of malignant tumors on their reproductive organs, in the form of ovarian and oviductal adenocarcinomas.
Laying hen oviduct
The high incidence of tumors (one study showed that 45% of 2 year old laying hens had tumors associated with the reproductive tract) are related to the extended maintenance of egg production in laying hen breeds. In the same study, 24% of all hens developed malignant ovarian adenocarcinomas by the time they were 2 years of age. The incidence of tumors increases with age, as hormone levels decrease.

As tumors enlarge, the lumen may become slit-like or filled by cribriform structures, often surrounded by dense fibrous connective tissue. It has often been described for it's resemblance to cauliflower, with irregular masses bulging outward from the central tumor and that usually replaces all of the normal ovarian structure. In advanced stages of the disease, tumor growth will extend into the abdomen, and grow on serosal surfaces of the oviduct, mesentery, and intestines, and on the pancreas. As the mesentery contracts and the bowel wall thickens, ascites develops, which appears as a soft, subcutaneous swelling around the hen's belly--also referred to as enlargement of the abdomen.


There is no available cure for ovarian cancer in hens. Treatment options are aimed at stopping egg production, to minimize risk of future egg-related infections (egg yolk peritonitis), which include hormonal implants or, as a last resort, "spaying". There are also a number of different natural herbs which have been documented to have certain anti-cancer properties and have been shown to be beneficial for some patients with ovarian tumors. These include:

Clinical Signs

Enlarged abdomen
Loss of appetite
Upright, penguin-like position


  • History
  • Clinical signs
  • Physical exam
  • Ultrasound
  • Laboratory tests


Hormone implantsSuprelorinĀ®, Virbac is used 'off-label' to stop ovulation (egg production) in hens.
Salpingohysterectomy (spaying)The surgical removal of the entire oviduct of the chicken.


Scientific References


Age Range

Occurs usually in mature egg laying hens over 2 years of age

Risk Factors

  • Chronic egg laying
  • Increased age
  • Poor quality diet