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Uropygial Gland Infections

The uropygial gland, also referred to as the preen gland or oil gland, is located at the base of the chicken's tail on their lower back, just in front of the tail feathers. This gland is responsible for secreting a thick, transparent oil which the bird spreads over their feathers (through the act of 'preening'). This oil consists of a combination of extruded cells, ester waxes, fatty acids, fat and sudanophilic secretory granules. It performs several important functions in birds, including:
  • Waterproofing
  • Suppression of growth of bacterial organisms on the skin through its antibacterial properties.
  • Manufacturing vitamin D precursors that are spread over the bird's feathers while they preen. With exposure ultraviolet rays produced by sunlight, the secretions convert to an active form (vitamin D3) which is then ingested with subsequent preening.
  • Maintaining quality of their skin, feathers, and beak.
Many uropygial gland abnormalities in chickens occur secondary to vitamin A deficiency, resulting in enlargement of the gland, glandular metaplasia, and hyperkeratosis.

Treatment of Uropygial Gland Infections

Treatment will depend on the cause. Most early cases of uropygial gland infections in chickens can be corrected by gently massaging or milking the gland after a moist hot compresses has been applied, in conjunction with diet changes. Sometimes an injection of parenteral vitamin A may be needed. Based on culture and sensitivity results, systemic antibiotic or antifungal therapy may be beneficial. Suspected tumors may require surgical excision.

Clinical Signs

Lack of or excessive preening behavior
Poor feather quality
Inability of feathers to become water resistant
Self-trauma and/or mutilation to the gland area
Large mass in area around uropygial gland


  • History
  • Evaluation of diet
  • Clinical signs
  • Physical exam
  • Cytology - of gland secretion
  • Bacterial culture
  • Biopsy of gland


Gently massaging or milking the gland after a moist hot compresses has been applied.
Diet changes
injection of parenteral vitamin A
Systemic antibiotic or antifungal therapy, selected based on culture and sensitivity results.
Surgical excisionIn cases of suspected tumors.



  • Ensure chickens receive good vitamin A rich sources in their daily diet.
  • Conduct annual fecal tests to screen for the presence of internal parasites.

Scientific References

Risk Factors

  • Vitamin A deficiency
  • Glandular or ductular neoplasia
  • Bacterial infection
  • Impaction of the gland
  • Trauma to uropygial gland
  • Self-mutilation/feather/picking around the gland