Attention! This is a potentially life-threatening condition for your bird and/or flock. Time is of the essence, contact your veterinarian immediately.Find me a Vet

Cyanide Poisoning

Hydrocyanic Acid Toxicity, Prussic Acid Poisoning

Cyanide is a highly potent, rapidly acting poison. Several common plants have the capability of accumulating large quantities of cyanogenic glycosides, which are found in the epidermal cells (outer tissue) of the plant. These plants also contain certain enzymes within the mesophyll cells (inner tissue) that upon rupture, mix with cyanogenic glycosides to produce cyanide. These plant cells are ruptured by wilting, drought, crushing, chewing, chopping, trampling, freezing, and cutting into the plant.

Upon ingestion of plant parts containing varying levels of cyanide, the toxin rapidly enters the chicken's blood stream where it is transported throughout the body of the bird.
Cyanide inhibits the use of oxygen by the cells in the body, resulting in death by suffocation.

Plants capable of producing high levels of cyanide: The amount of cyanide found in these plants varies depending on the plant part, season, stage of growth of the plant, whether herbicides were recently used, and environmental conditions. Drought and frost or freezing are stressful conditions that increase the risk of high levels of cyanide accumulation in affected plants. Any stressful condition that inhibits the growth of the plant can cause higher amounts of cyanide to develop. New plant growth also has higher levels of cyanide then mature plants. Leaves of cyanide-accumulating forage grasses produce 25 times more cyanide than the stems.

Chickens that die from cyanide poisoning have bright red, oxygenated blood and bodily tissues are usually congested with blood. The reported oral LD50 for domestic chickens is 11.1 mg/kg of body weight. Chickens will usually die within 15 to 30 minutes of ingestion of the toxic substance.


Eye blinking
Blue-purple colored comb
Sudden death


  • History
  • Clinical signs
  • Physical exam
  • Laboratory tests


Supportive care: Isolate the bird from the flock and place in a safe, comfortable, warm location (your own chicken "intensive care unit") with easy access to water and food. Limit stress. Call your veterinarian immediately.




Scientific References

Risk Factors

  • Feeding chickens large amounts of apples (containing seeds), apricots, peaches, almonds, cassava root or cherries