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The chicken's respiratory system is particularly sensitive to exposure to airborne toxins. This is related to the uniqueness of the avian respiratory system, and actually allows for birds to breath more effectively then mammals. The cross-current airflow and blood allows for the chicken's blood oxygen levels to be higher than their oxygen levels when they expire a breath. The negative consequence of this is it increases their risk of absorbing higher amounts of toxins from the air, thus causing them to reach toxic levels quicker than mammals. Clinical signs may be delayed several hours after the initial exposure.