|1000 mg/kg of diet
|antibacterial, Salmonella pullorum
|alleviated S. pullorum-induced intestinal disruption and performance impairment in laying hens, which could be at least partially responsible by the modulation of gut microbial composition.
|W Wang et al., 2020
|effectively decreased gut inflammation and increased chicken performance.
|K Varmuzova et al., 2015
|0.5-1.5% of diet
|should be carefully evaluated when given to poultry. The excess intake may cause immunologic inhibition and may negatively affect the development of immune organs. Can inhibit the formation of radial segmentation nuclei showing antimetastatic properties and also the phagocytosis of chicken heterophils.
|B Kroliczewska et al., 2017
|100 to 200 mg/kg of diet
|can be used as an effective natural feed additive in broiler chicken diets.
|Y Zhou et al., 2019
|has a protective effect against mycoplasma-induced lung inflammation in chicken by inhibiting the TLR6-mediated NF-B signalling.
|M Zou et al., 2020
|antiviral, Avian influenza virus
|results provide a new theoretical basis for clinical prevention and control of H9N2 AIV infection-induced secondary bacterial infection and inflammation.
|X Zhang et al., 2020
|450 mg/kg of diet
|Histopathological examination showed the alveolar spaces and mucosal layer thickening was restored and cilia gradually recovered with baicalin treatment compared in coinfection group and MG-infection group. Meanwhile, IL-17 singling pathway–related genes were significantly reduced in baicalin treatment group in lung, including IL-17C, TRAF6, NF-B, CXCL1, CXCL2, MMP1, GM-CSF, and MUC5AC.
|Z Wu et al.,2020
|antiviral, Duck virus hepatitis
|possessed anti-DHAV-1 effect. It improved the cytoactive of DEH which was infected by DHAV-1 as well as reduced the DHAV-1 reproduction in DEH. Under baicalin treatment, mortality of ducklings infected by DHAV-1 decreased, additionally the DHAV-1 level and liver injury in such ducklings were significantly reduced or alleviated. The in vitro mechanism study indicated baicalin inhibited DHAV-1 reproduction via interfering the viral replication and release. Furthermore, the in vivo mechanism study manifested both the anti-oxidative and immuno-enhancing abilities of baicalin, which played crucial roles in its curative effect on DVH.
|Y Chen et al., 2019
|promoted mitochondrial dynamics imbalance and effectively prevents oxidative stress and apoptosis in the splenocytes of chickens infected with mycoplasma.
|M Ishfaq et al., 2020
|10 to 20 mg/kg diet
|exerts a protective effect against APEC-induced intestinal injury in chicks by inhibiting the PI3K/AKT-mediated NF-B pathway, suggesting that BA may be a potential therapeutic approach for avian colibacillosis.
|X Cheng et al., 2022
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