Brand Names:
Protopam Chloride

Drug Type: Antitoxin

Pralidoxime mesylate

Pralidoxime is used in the treatment of organophosphate poisoning, of­ten in conjunction with atropine and supportive therapy. Pralidoxime is only marginally absorbed after oral dosing and oral dosage forms are no longer available in the United States.

Storage/Stability: Unless otherwise instructed by the manufacturer, prali­doxime chloride powder for injection should be stored at room temperature. After reconsti­tuting with sterile water for injection, the solution should be used within a few hours. Do not use sterile water with preservatives added.
  • 100 mg/kg IM. Repeat once after 6 hours.