Ceftriaxone is a broad-spectrum cephalosporin/cephamycin beta-lactam injectable antibiotic. It is used in the treatment of bacterial infections caused by susceptible, usually gram-positive organisms.
Note: Cephalosporins may disturb the normal intestinal microflora of poultry, particularly when administered orally and at high doses.
Storage
Store powder for injection at or below 25° C (77° F). Protect from light. The color of solution ranges from light yellow to amber, depending on concentration, length of storage, and diluent. Once mixed, intramuscular (IM) and IV solutions remain >90% potent for up to 10 days if refrigerated at 4° C (39° F). Potency is affected by diluent, concentration, and temperature. IM and IV preparations may maintain >90% stability for as little as 1 or 3 days, respectively, at room temperature. If reconstituted with 5% dextrose or 0.9% sodium chloride solution and then frozen at −20° C (−4° F), preparations have been stable for 26 weeks in PVC or polyolefin containers. Thaw at room temperature before using. Unused thawed solutions should be discarded. Do not refreeze. Ceftriaxone may be incompatible with other antimicrobials; do not mix.
