Drug Type: Antiinflammatory, Analgesic

Carprofen

Carprofen is an oral or injectable analgesic anti-inflammatory medication given 'off-label' to pet poultry for pain relief. It belongs to a class of drugs referred to as non-steroidal anti-inflammatory drugs (NSAIDs). It is most frequently prescribed for treatment of minor or chronic pain and inflammation resulting from conditions such as chronic arthritis. It is also given to birds during post-surgical recovery. Peak plasma levels of subcutaneously injected carprofen are reached 1 to 2 hours.

Caution!
  • Carprofen should not be given with other NSAIDs (meloxicam), aspirin, prednisone or dexamethasone. It significantly increases the risk of ulcers and internal bleeding. There should be period of at least 24 hours when switching between these medications.
  • Carprofen should not be given with diuretics or other nephrotoxic drugs that increase the risk of kidney damage.
  • Carprofen can interfere with ACE inhibitors (like enalapril or benazepril) and their ability to prevent heart failure.

Storage: Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° and 30°C (59° and 86°F) [see USP Controlled Room Temperature]. Use within 90 days of splitting.

Disclaimer: Use at your own risk. We assume no responsibility for the use of the drug, dosages given and for any misstatement, error, negligent, or otherwise.
  • 30 mg/kg IM (B Speer 2016)
Oral tablets or injectable
  • Diarrhea
  • Aspirin: The risk or severity of adverse effects can be increased when Carprofen is combined with Acetylsalicylic acid.
  • Allopurinol: Carprofen may decrease the excretion rate of Allopurinol which could result in a higher serum level.
  • Amikacin: Carprofen may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Amoxicillin: Carprofen may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
  • Ampicillin: Carprofen may decrease the excretion rate of Ampicillin which could result in a higher serum level.
  • Bismuth subsalicylate: The therapeutic efficacy of Bismuth subsalicylate can be decreased when used in combination with Carprofen.
  • Cefadroxil: Carprofen may decrease the excretion rate of Cefadroxil which could result in a higher serum level.
  • Cefapirin: The risk or severity of nephrotoxicity can be increased when Carprofen is combined with Cefapirin.
  • Cephalexin: Carprofen may decrease the excretion rate of Cephalexin which could result in a higher serum level.
  • Dexamethasone: The risk or severity of gastrointestinal irritation can be increased when Dexamethasone is combined with Carprofen.
  • Dextran: The risk or severity of bleeding and hemorrhage can be increased when Carprofen is combined with Dextran.
  • Diazepam: Carprofen may decrease the excretion rate of Diazepam which could result in a higher serum level.
  • Diclofenac: The risk or severity of adverse effects can be increased when Diclofenac is combined with Carprofen.
  • Dihydrostreptomycin: The risk or severity of nephrotoxicity can be increased when Carprofen is combined with Dihydrostreptomycin.
  • Dimethyl sulfoxide:Carprofen may decrease the excretion rate of Dimethyl sulfoxide which could result in a higher serum level.
  • Doxycycline: Carprofen may decrease the excretion rate of Doxycycline which could result in a higher serum level.
  • Enalapril:The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Carprofen is combined with Enalapril.
  • Enrofloxacin:Carprofen may increase the neuroexcitatory activities of Enrofloxacin.
  • Magnesium sulfate:The risk or severity of hyperkalemia can be increased when Magnesium sulfate is combined with Carprofen.
  • Meloxicam: Significantly increases the risk or severity of adverse effects when Meloxicam is combined with Carprofen.
  • Methylprednisolone:The risk or severity of gastrointestinal irritation can be increased when Methylprednisolone is combined with Carprofen.
  • Prednisolone:The risk or severity of gastrointestinal irritation can be increased when Prednisolone is combined with Carprofen.
  • Prednisone:The risk or severity of gastrointestinal irritation can be increased when Carprofen is combined with Prednisone.
  • Salicylic acid:The risk or severity of adverse effects can be increased when Carprofen is combined with Salicylic acid.
  • Selenium:Carprofen may decrease the excretion rate of Selenium which could result in a higher serum level.
  • Sulfadiazine:Carprofen may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
  • Tetracycline:Carprofen may decrease the excretion rate of Tetracycline which could result in a higher serum level.

Popular Health Tools

Switch Animal