Grape seed extract (GSE) is a potent antioxidant which is made from the seeds of grapes. It is also one of the best-known sources of proanthocyanidins. Its high antioxidant content is well-known for its benefits associated with disease prevention and protection against oxidative stress, tissue damage, and inflammation. GSE also inhibits the growth of Campylobacter, E. coli, Staphylococcus aureus bacteria and Candida fungi.
Research conducted on the addition of GSE to the diet of chickens have showed positive results for it’s use as a potent antioxidant and immune enhancer when supplemented to their diet. Farahat, M. H., et al., 2017 recommended adding it at a rate of 125 to 250 ppm as the optimum dosage. 250-500 mg/kg showed protective effects against liver damage caused by aflatoxicosis (S Rajput et al., 2018). 12 mg/kg was beneficial for chickens with coccidiosis (Wang, M. L., et al., 2008).