Brand Names:
Baytril, Enrotril


Drug Type: Antibiotic

Enrofloxacin (Baytril, Enrotril)


Enrofloxacin (Baytril, Enrotril) is a fluroquinolone, broad-spectrum antibiotic which is useful for treating a wide range of bacterial infections in birds. Baytril is the veterinary-labeled form of ciprofloxacin, which is also a fluroquinolone antibiotic used in humans. Fluroquinolone antibiotics are the drug of choice against Mycoplasma, some gram-positive bacteria, and most gram-negative bacteria (includes Escherichia coli, and Salmonella).

Form: Baytril is available in tablet form, as an injection and as an oral syrup. The oral syrup can be given directly to the mouth or dissolved in the drinking water. Due to its bitter taste, it may be necessary to mix the drug with another medium such as apple sauce or fruit juice to improve the taste. The drug is less effective when administered in drinking water.

Caution: Poultry taking this medication should be concurrently monitored for signs of secondary infections, especially those caused by yeast (sour crop). Treating young, growing birds with Baytril may cause permanent damage to their joints. Baytril can interfere with cartilage deposition on the surface of the joints which may lead to permanent deformity.

Treating birds with fungal infections with Baytril will make the infection worse.

Egg Withdrawal Period: Enrofloxacin should not be used in female poultry producing eggs intended for human consumption. The drug does not have a maximum residue limit for eggs.

Typical Dosage: 10-30 mg/kg given twice daily, by mouth, usually for 3-5 consecutive days. The later (5 days), is usually indicated for birds with mixed infections and/or chronic progressive forms of infection. If there are no signs of improvement within the first 2-3 days, an alternate antibiotic should be considered and selected based on susceptibility testing.

If administered in drinking water, the recommended doses are 100-200 ppm (0.1-0.2 mg/ml).

Storage: Enrofloxacin can remain physically and chemically stable over a 48 month storage period. However, once opened, the drug should be discarded after 12 weeks. If diluted in water, it should be discarded after 24 hours.
  • Muscle necrosis at the injection site, if given IM
  • Behavioral changes
  • Secondary infections