Brand Names:

Drug Type: Antibiotic


Enrofloxacin (Baytril) is a fluroquinolone antibiotic used to treat bacterial infections in poultry caused by Avibacterium paragallinarum, Escherichia coli, Mycoplasma gallisepticum, M. synoviae, and Pasteurella multocida. It is one of the main drugs of choice for the treatment of Septicaemia, Chlamydiosis, Colibacillosis, Mycobacteriosis, and Mycoplasmosis in poultry. Baytril is the veterinary-labeled form of Ciprofloxacin, an antibiotic made for humans.

Forms: Enrofloxacin is available in liquid (20 or 100 mg/mL), or tablet (5.7, 22.7 or 68 mg) form. Due to its bitter taste, it may be necessary to mix the drug with another medium such as apple sauce or fruit juice to improve the taste. The drug is less effective when administered in drinking water.

Caution: Poultry taking this medication should be concurrently monitored for signs of secondary infections, especially those caused by yeast (sour crop). Take caution when giving this drug to growing birds, as can cause damage to the articular cartilage in their bones.

Withdrawal Period: Enrofloxacin should not be used in female poultry producing eggs intended for human consumption. The drug does not have a maximum residue limit for eggs.

Typical Dosage: 10 mg/kg bodyweight per day for 3-5 consecutive days. The later (5 days), is usually indicated for birds with mixed infections and/or chronic progressive forms of infection. If there are no signs of improvement within the first 2-3 days, an alternate antibiotic should be considered and selected based on susceptibility testing.

Instructions for Administering in Drinking Water:
  • Make sure that the entire dose offered has been consumed.
  • The medicated water should be made up fresh each day, just before it is offered to the bird.
  • The drinking water must remain medicated throughout the duration of the treatment period (3-5 days), and no other water source should be available.
  • In order to calculate the correct dosage, the bird must be weighed and converted to kg.
  • Use the following equation to calculate the daily quantity in mL of "Product name" required for treatment period as follows:

    Total number of birds x Average body weight in kg x 01 = Total volume (mL) per day
Shelf life: Enrofloxacin can remain physically and chemically stable over a 48 month storage period. However, once opened, the drug should be discarded after 12 weeks. If diluted in water, it should be discarded after 24 hours.
  • Muscle necrosis at the injection site, if given IM
  • Behavioral changes
  • Secondary infections