Brand Names:
Valium, Diastat, Diazemuls, Nervium


Drug Type: Anesthetic, Anticonvulsant, Appetite_stimulant, Sedative

Diazepam

Diazepam is a drug of the benzodiazepine class that is used clinically for its anxiolytic, muscle relaxant, hypnotic, appetite stimulant, and anticonvulsant activities. Diazepam is rapidly absorbed following oral administration. Peak plasma levels occur within 30 minutes to 2 hours after oral dosing. The drug is slowly (slower than oral) and incompletely absorbed following IM administration.

Caution: Diazepam should never be combined with depressants such as opiates, barbiturates, gabapentinoids, alcohol or other GABAergic substances---which can cause death.

Storage/Stability: All diazepam products should be stored at room temperature (15°-30°C). The injection should be kept from freezing and protected from light. The oral dosage forms (tablets/capsules) should be stored in tight containers and protected from light. Because diazepam may adsorb to plastic, it should not be stored drawn up into plastic syringes.
  • 0.25-0.50 mg/kg IM, IV q24h for 2-3 days.
  • Increase intraocular pressure, predisposing the bird to developing glaucoma
  • Hypotension
  • Kidney and liver damage
  • Chloramphenicol:The metabolism of Diazepam can be decreased when combined with Chloramphenicol.
  • Chloroquine: The serum concentration of Diazepam can be increased when it is combined with Chloroquine.
  • Chlorpromazine: The serum concentration of Diazepam can be increased when it is combined with Chlorpromazine
  • Clotrimazole:The metabolism of Diazepam can be decreased when combined with Clotrimazole.
  • Dexamethasone:The serum concentration of Diazepam can be decreased when it is combined with Dexamethasone.
  • Ivermectin: The serum concentration of Diazepam can be increased when it is combined with Ivermectin.
  • Ketoconazole:The metabolism of Diazepam can be decreased when combined with Ketoconazole.
  • Magnesium Sulfate: Magnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Diazepam.