Brand Names:
Amoxinsol, Amoxil


Drug Type: Antibiotic

Amoxicillin

Amoxicillin is a broad spectrum penicillin antibiotic used to treat certain bacterial infections in poultry. Amoxicillin has activity against penicillin-sensitive Gram-positive bacteria, as well as some Gram-negative bacteria. The gram-positive spectrum of activity includes alpha- and beta-hemolytic streptococci, some Staphylococci species, and Clostridia species. Amoxicillin is also effective against Escherichia coli (E. coli), many strains of Salmonella, and Pasteurella multocida.

Amoxicillin is most commonly given to birds who were recently attacked by a predator, to help prevent pasteurellosis (fowl cholera) from bites or scratches.

Egg Withdrawal Period: 1 day withdrawal period for eating eggs.

Storage/Stability: Amoxicillin capsules, tablets, and powder for oral suspension should be stored at room temperature (15-30°C) in tight containers. After reconstitution, the oral suspension should preferably be refrigerated (refrigeration not absolutely necessary) and any unused product discarded after 14 days. After reconstitution, the injectable veterinary suspension is stable for 3 months at room temperature and 12 months when refrigerated.
  • Amoxicillin/clavulanate - 125-250 mg/kg PO q8-12h or 500 mg/L drinking water (B Speer).
  • Amoxicillin sodium - 50-250 mg/kg IM, IV q8-12h (B Speer).
  • Amoxicillin trihydrate - 55-200 mg/kg PO, SC, IM, IV q4-12 h or 200-1500 mg/L drinking water (B Speer).
tablets, suspension, powder, syrup, injection (powder solution)
  • Will decrease potassium levels in the blood (hypokalemia)
  • Acetylsalicylic acid: Acetylsalicylic acid may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
  • Acyclovir: Acyclovir may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
  • Amikacin: Amoxicillin may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Allopurinol: The risk of a hypersensitivity reaction to Amoxicillin is increased when it is combined with Allopurinol.
  • Amphotericin B: Amphotericin B may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
  • Ampicillin: Ampicillin may decrease the excretion rate of Amoxicillin which could result in a higher serum level.