Brand Names:
Zovirax, Zovir


Drug Type: Antiviral

Acyclovir (Zorirax)


Acyclovir (also referred to as aciclovirum or acycloguanosine) is an antiviral drug used to treat herpes simplex virus infections. In humans, acyclovir is used to treat the varicella zoster virus (chickenpox) and herpes zoster virus (shingles). Since Marek's disease virus is also a herpes virus, it has been studied for it's use in the treatment of Marek's Disease in birds. It works by interfering with the synthesis of the virus’ DNA.

Drug Form. Acyclovir is available as tablets (400 and 800 mg), powder (50 mg/ml), oral suspension (40 mg/ml), or 200 mg capsules.

Typical Dosage: 80 mg/kg given 3 times a day orally. If given in food, can be up to 240 mg/kg.
  • Kidney damage
  • Increased thirst
  • Lethargy
  • Seizures
  • Tremors
  • Coma
  • Behavioral changes
  • Teriflunomide: The serum concentration of Aciclovir can be increased when it is combined with Teriflunomide.
  • Tizanidine: The serum concentration of Tizanidine can be increased when it is combined with Aciclovir.