Brand Names:
Zovirax, Zovir, Burroughs, Wellcome


Drug Type: Antiviral

Acyclovir (Zorirax)


Acyclovir is an antiviral drug used to treat herpes simplex virus infections. In humans, acyclovir is used to treat the varicella zoster virus (chickenpox) and herpes zoster virus (shingles). Since Marek's disease virus is also a herpes virus, it has been studied for it s use in the treatment of Marek's Disease in birds. It works by interfering with the synthesis of the virus’ DNA.
Available as tablets (400 and 800 mg), powder (50 mg/ml), oral suspension (40 mg/ml), or 200 mg capsules.
10 mg/kg IM q24h x 5-14 days
  • Severe muscle necrosis
  • Kidney damage
  • Increased thirst
  • Lethargy
  • Seizures
  • Tremors
  • Coma
  • Behavioral changes
  • Teriflunomide: The serum concentration of Aciclovir can be increased when it is combined with Teriflunomide.
  • Tizanidine: The serum concentration of Tizanidine can be increased when it is combined with Aciclovir.