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Oosporein Mycotoxicosis

Oosporein Toxicity

Oosporein is a nephrotoxic mycotoxin produced by Chaetomium, Acremonium, Penicillium, Oospora, and spp of fungi. Chickens are more sensitive to oosporein then other animals. It is associated with impaired renal function and increased plasma concentrations of uric acid, resulting in an increased risk of chickens' developing gout and renal failure. The acute single oral LD50 of oosporein if 4.56 mg/kg body weight in day-old broiler chicks.

The chronic affects of oosporein mycotoxicosis are very similar in appearance to chronic toxicosis induced by citrinin, ochratoxin A, and aflatoxins.

Clinical Signs

Increased thirst
Renal failure


  • History
  • Clinical signs
  • Feed analysis
  • Necropsy


Supportive care: Isolate the bird from the flock and place in a safe, comfortable, warm location (your own chicken "intensive care unit") with easy access to water and food. Limit stress. Call your veterinarian.



Properly store feed

Scientific References

    Risk Factors

    • Purchasing poor quality feed
    • Improper storage of feed