Wild rue (Peganum harmala
) is widely distributed and used as a medicinal plant in Central Asia, North Africa and Middle East. Dried wild rue fruit is used by Iranians and Turkish cultures as an amulet or charm against evil eye. Wild rue chemical components include several types of beta-carboline and quinazoline alkaloids (harmine, harmaline, Harman and harmalol). Since ancient times, wild rue has been used by numerous cultures for the treatment of cancers and tumors.
The crude extract of P. harmala
possesses some antibacterial effects against E. coli, S. aureus, P. aeruginosa, K. pneumoniae
and P. vulgaris
Wild rue has showed to be of use in control of Coccidiosis
in broiler chicks when added at a rate of 200-300 mg/L to drinking water for 14 days.