Goldenseal (Hydrastis Canadensis) is a plant native to North America which contains a compound called berberine. It is used as a dietary supplement for colds and other respiratory tract infections, allergic rhinitis, ulcers, and digestive upsets such as diarrhea and constipation in humans. The roots of goldenseal are dried and used to make teas, extracts, tablets, or capsules.
Miraghaee, S. S., Heidary, B., Almasi, H., Shabani, A., Elahi, M., & Nia, M. H. M. . "The effects of Nigella sativa powder (black seed) and Echinacea purpurea (L.) Moench extract on performance, some blood biochemical and hematological parameter" African Journal of Biotechnology (2011)