Sulfadimethoxine is a sulfonamide antibiotic used to treat Coccidia infection in poultry. It is usually used in combination with other antibiotics, such as trimethoprim or ormetoprim. The sulfa class of antibiotics work by depriving the bacteria of the folic acid they need without interfering with the folic acid available to the host. The sulfa or “sulfonamide” class of antibiotics has earned a special place in history as the very first antibiotics ever developed and for the first time in human history domination over bacterial infection became readily feasible.
Form: The drug comes available as 125 mg, 250 mg, or 500 mg tablets and oral suspension.
Egg Withdrawal Period: Sulfadimethoxine should not be given to poultry producing eggs intended for human consumption in any country, due to the lack of studies on the duration of residues in the eggs of treated hens.
Caution: Sulfadimethoxine can precipitate in urine forming crystals or even stones, leading to kidney damage and gout. This is typically a problem with prolonged use or acidified urine. Sulfa drugs should not be given to birds with liver or kidney problems.