Neomycin is an aminoglycoside antibiotic. Neomycin has a mechanism of action and spectrum of activity (primarily gram negative aerobes) similar to the other aminoglycosides, but in comparison to either gentamicin or amikacin, it is significantly less effective against several species of gram negative organisms, including strains of Klebsiella, E. coli and Pseudomonas. Neomycin is poorly absorbed from the gastrointestinal tract of birds and a low acute toxicity after oral administration. It is often added to medicated poultry feeds.
Caution: Neomycin should not used in combination with Amphotericin B or Penicillins due to increased risk of renal damage and low potassium blood levels.
Egg Withdrawal Period: 14 days
Storage/Stability: Neomycin sulfate oral solution should be stored at room temperature (15-30°C) in tight, light-resistant containers. Unless otherwise instructed by the manufacturer, oral tablets/boluses should be stored in tight containers at room temperature. The sterile powder should be stored at room temperature and protected from light. In the dry state, neomycin is stable for at least 2 years at room temperature.
