Marbofloxacin is a synthetic, broad-spectrum antibiotic that is classified as a fluoroquinolone drug. It is similar to enrofloxacin and used in veterinary medicine to treat an array of serious bacterial infections mainly in ducks. Studies have shown that in Muscovy ducks, marbofloxacin had a good oral bioavailability (72 to 88%).
Marbofloxacin’s primary mechanism of action is to inhibit the bacterial enzymes, which eventually leads to the death of the bacteria.
Form: Marbofloxacin is only available with a prescription from a veterinarian and it can be obtained through a veterinary compounding pharmacy in either oral or transdermal formulations. Many different strengths are available in compounded form.
Typical dosage: The recommended dosage in ducks are 2-2.5 mg/kg daily, given orally for the treatment of most Gram-negative bacteria.
Caution: Marbofloxacin should be avoided in very young birds, as it can cause damage to joint cartilage. It should be used with extreme caution in animals with pre-existing disorders of the brain or spinal cord.