Brand Names:
Eligard, Lupron, Lupron Depot, Viadur, Depo Lupron

Drug Type: GnRH-agonist, Hormone

Leuprolide acetate (Lupron)

Leuprolide acetate (Lupron) is a type of gonadotropin-releasing hormone (GnRH) agonist. It is used for hormone therapy in poultry with reproductive disorders. It accomplishes this by stopping them from laying eggs by stopping the ovaries from making estrogen and progesterone. Leuprolide acetate has also been used in overly aggressive roosters with excessive sex drives. It acts by preventing their bodies from making more testosterone. Roosters who have received the injection or implant usually initially undergo an increase in testosterone level for the first week, then start to decline by the end of the second week of treatment.
Leuprolide acetate is given as an intramuscular (IM) injection or subcutaneously implanted, under the skin.
500-800 µg/kg IM, administered every 14 days. Usually after 3 doses it begins to take effect.
  • Reduced bone density, resulting in increased risk of fractures
  • Poor feather quality