Lactulose

Overview

Lactulose is mainly used in the management of hepatic encephalopathy to reduce production and absorption of ammonia from the gastrointestinal tract. May be indicated for certain cases of liver disease. May also be effective as an appetite stimulant.

Dosage

0.3 mL/kg PO q12h

Drug Form

oral suspension

Side Effects

Diarrhea

Drug Interactions

L-Glutamine:The therapeutic efficacy of Lactulose can be decreased when used in combination with L-Glutamine.

References

Cho, J. H., and I. H. Kim. Effects of lactulose supplementation on performance, blood profiles, excreta microbial shedding of Lactobacillus and Escherichia coli, relative organ weight and excreta noxious gas contents in broilers Journal of Animal Physiology and Animal Nutrition 98.3 (2014)
Totton, Sarah C., et al. The effectiveness of selected feed and water additives for reducing Salmonella spp. of public health importance in broiler chickens: a systematic review, meta-analysis, and meta-regression approach Preventive veterinary medicine 106.3-4 (2012)
Grunkemeyer, Vanessa L. Advanced diagnostic approaches and current management of avian hepatic disorders Veterinary Clinics: Exotic Animal Practice 13.3 (2010)
Vandeplas, Sabrina, et al.. Salmonella in chicken: current and developing strategies to reduce contamination at farm level Journal of food protection 73.4 (2010)
Doneley, Bob. Treating liver disease in the avian patient Seminars in avian and exotic pet medicine. Vol. 13. No. 1. WB Saunders (2004)
Hughes, Robert J. Energy metabolism of chickens: physiological limitations. RIRDC (2003)
Wheler, Colette L., and Rodney A. Webber. Localized ascites in a cockatiel (Nymphicus hollandicus) with hepatic cirrhosis Journal of avian medicine and surgery 16.4 (2002)

Lactulose

Overview

Dosage

Drug Form

Side Effects

Drug Interactions

References

PoultryDVM.com

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