Brand Names:
Rocephin, Epicephin


Drug Type: Antibiotic

Ceftriaxone (Rocephin)


Ceftriaxone, sold under the brand Rocephin, is a broad-spectrum cephalosporin/cephamycin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. Ceftriaxone has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.
75-100 mg/kg IM q4-8h
  • Amikacin:Ceftriaxone may increase the nephrotoxic activities of Amikacin.
  • Apramycin: Ceftriaxone may increase the nephrotoxic activities of Apramycin.
  • Calcium: The risk or severity of adverse effects can be increased when Calcium is combined with Ceftriaxone.
  • Gentamicin: Ceftriaxone may increase the nephrotoxic activities of Gentamicin.
  • Neomycin:Ceftriaxone may increase the nephrotoxic activities of Neomycin.
  • Streptomycin: Ceftriaxone may increase the nephrotoxic activities of Streptomycin