Brand Names:
Atropine sulfate

Drug Type: Anesthetic, Anticholinergic, Antitoxin


Atropine is a drug used to treat eye conditions, certain heart disorders, poisoning, and a few gastrointestinal conditions. Atropine is in a class of drugs known as anticholinergics. It works by blocking the actions of acetylcholine, a neurotransmitter that helps move electrical impulses among nerve cells.

Atropine is administered during poisoning by pesticides and certain toxic plants (Azaleas (Rhododendron), mushrooms (False Morel Mushroom (Gyromitra), Mower's Mushroom (Gymnopilus), Common Toadstool Mushroom (Gymnopilus), and poisoning associated with bradycardia hyptension.

Drug Form: Atropine comes available as an injectable solution (0.5 mg/ml or 15 mg/ml).

Typical Dosage: 0.01-0.02 mg/kg given IV or IM every 3-4 hours.

Caution. Excessive or inappropriate use can cause heart arrhythmias and death.
  • Cardiac arrhythmias
  • Gastrointestinal stasis
  • Increased heartrate
  • Restlessness
  • Abdominal swelling
  • Depression
  • Change in balance
  • Difficulty breathing
  • Lethargy
  • Belladonna (Donnatal, and others)
  • Benztropine (Cogentin)
  • Dimenhydrinate (Dramamine)
  • Methscopolamine (Pamine)
  • Scopolamine (Transderm-Scop)
  • Bronchodilators : such as ipratropium (Atrovent, Combivent) or tiotropium (Spiriva)
  • Digoxin (digitalis, Lanoxin)
  • Glycopyrrolate (Robinul)
  • Mepenzolate (Cantil)
  • Bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare)
  • Irritable bowel medicines such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine)