Brand Names:
AmiJect D, Amikacin K-9


Drug Type: Antibiotic, Antibacterial

Amikacin (AmiJect D, Amikacin K-9)


Amikacin (AmiJect D, Amikacin K-9) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. It is very potent and usually only used as a last resort in birds, due to it s nephrotoxic and ototoxic properties. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. Amikacin may also be used to treat Mycobacterium avium infections. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Caution: Be sure to prevent birds from becoming dehydrated while taking this medication, for there is a high risk of kidney damage.
comes as an injectable solution (50 mg/ml and 250 mg/ml), given IM or SC.
5-6 mg/ml sterile water or saline x 15 min q8-12h
  • Dehydration
  • Kidney damage
  • Acetylsalicylic acid:Acetylsalicylic acid may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Amoxicillin: The serum concentration of Amikacin can be decreased when it is combined with Amoxicillin.
  • Amphotericin B: Amphotericin B may increase the nephrotoxic activities of Amikacin.
  • Ampicillin:The serum concentration of Amikacin can be decreased when it is combined with Ampicillin.
  • Carprofen: Carprofen may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Celecoxib:Celecoxib may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Chloroquine: Chloroquine may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Cloxacillin:The serum concentration of Amikacin can be decreased when it is combined with Cloxacillin.
  • Curcumin:Curcumin may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Evening primrose oil:Evening primrose oil may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Furosemide:The risk or severity of adverse effects can be increased when Furosemide is combined with Amikacin.
  • Flunixin:Flunixin may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Meloxicam:Meloxicam may decrease the excretion rate of Amikacin which could result in a higher serum level.
  • Phenylbutazone:Phenylbutazone may decrease the excretion rate of Amikacin which could result in a higher serum level.